A number of users are reporting an error message when they try to open any Office applications:
The operating system is not presently configured to run this application
This is apparently caused by an update to Norton security software. Either uninstall Norton or make this change:
- Open Norton's Settings, then Firewall
- Select Intrusion and Browser Protection.
- Disable Exploit Prevention.
- Create an appointment to remind you to enable Exploit Protection in a few weeks.
A bad Office update is also causing problems for some users. Uninstall March 28, 2017, update for Excel 2010 (KB3191855) if you have problems using Excel.
I have the same error message when opening Outlook 2016 but not other Office apps. Outlook SEEMS to run OK but message persists. Started yesterday after Outlook stopped mid use and updated. Microsoft Office Home and Business 2016 now showing as 18/03/2018 but not showing in program updates. I am running McAfee on 64 bit and W10 Home. Any help please?
Is this still a problem? Are you using any addins, including iCloud?
The problem has been ongoing with Norton products installed - one update fixes it, another seems to break it, but you aren't using Norton...
This worked!!! Thank God for the internet! Thank you!!!
This fixed my problem of not being able to open Office. However, if I reenable
EXPLOIT PROTECTION late, won't the same problem occur with Office?
you'll enable it again after Norton releases an update to fix it. I'd try it every couple of weeks or after you know they installed a software update (not just malware/spam definitions).