Signatures are stored in the roaming section of the windows profile, under %appdata%\microsoft\signatures. You can push signature updates into these folders using a Windows Scripting Host (WSH) script.
You can create signatures using AD data, either using a script or a utility.
Signature assignments are in the registry at HKEY_CURRENT_USER\Software\Microsoft\Office\xx.0\Common\MailSettings\ (where xx = your version of Office). This key is in the Outlook .adm file under Outlook, Tools, Options, Mail Format, Signature.
Alternately, you can add disclaimers to all messages using Exchange transport rules (Exchange 2007/2010) or with utilities installed on the Exchange or SMTP server. Cloud-based signature services are available for Office 365.
Tools in the Spotlight
CodeTwo Email Signatures for Office 365 is an easy to use signature manager for Office 365. This cloud-based solution fully integrates with your Office 365 tenant and enables central management of users' email signatures directly in the cloud. It has some unique features that make central email signature management in Office 365 a breeze, e.g.: HTML editor, signatures visible in Sent Items, support for email clients (including mobiles), user photos in signatures and more. The solution can be tested for free for 14 days.
With Exclaimer Cloud - Signatures for Office 365, all email is guaranteed to get a full, dynamic and professional email signature when sent from any device, including Macs and mobiles. It also allows for easy management of specific email signature elements including social media icons, promotional banners and legal disclaimers from one intuitive web portal. Sign up for a free 14 day trial today.
Use eMailSignature to create, design and manage email signatures centrally. Ensure company logos and merge employee information from Active Directory or other data source. Signatures are visible before sending. Automatic RTF and TEXT version creation and no installations on clients or Exchange Server required. Simple deployment through logon script or GPO. Extra modules for deploying vCards, campaigns, disclaimers and much more. Central administration through an administrative interface with built-in security. Free trial.
Exclaimer Signature Manager is the multi-award-winning solution for centrally managing and deploying Outlook, OWA and Office 365 signatures. There's nothing to install at the client and no Outlook add-ins are required. The powerful editor lets you combine images, text and fields to create compelling signatures. With our flexible and intuitive rules engine, you can assign different signatures based on AD groups, OU or any other attribute. Download a free, fully featured trial.
Using FastTrack Outlook Signatures, you can deploy automated signatures to all your clients. The signatures are designed in a program very similar to Word, which makes it really easy to keep all your clients signatures appear consistent and professional. Use any Active Directory (or Azure AD or Office 365) attribute, including photos, in the signatures.
Deploy standardized signatures and disclaimers to Outlook and Outlook Web Access, pulling contact information from Active Directory or a database. Does not require software installation or changes to servers or workstations. Deploy via logon script or AD. Signatures visible to users in both Outlook and Outlook Web Access. Built-in editor for designing HTML, RTF and Plain Text signature and disclaimer templates. Include the same disclaimer with different signatures, and include scheduled news, marketing or special offers in signatures. Supports Outlook stationery. Free evaluation version.
Auto generate Outlook Signature VB Script (TechNet forums)
Sample script to create a Signature from AD information
Disclaimer & Signature Tools for Microsoft Exchange Server
How to Configure a Disclaimer (Exchange 2007)
Understanding Disclaimers (Exchange 2010)